1. In spite of the fact it was Monday morning, he felt really good.
2. In spite of the cold, he felt really good.
3. Although he had a temperature, he felt really good.
4. Despite the fact he had no money, he felt really good.
5. In spite of his terrible headache, he felt really good.
6. Even though he was late for the meeting, he felt really good.
7. In spite of his being ill, he felt really good.
8. Although business was bad, he felt really good.
9. In spite of it being cold he felt really good.
10. In spite of the fact it was raining, he felt really good.